A 24-year-old woman with a history of brittle asthma is brought to the Emergency Department by her boyfriend. She is very short of breath and wheezy, and her condition deteriorates rapidly. Following back-to-back nebs, hydrocortisone and IV magnesium sulphate, she is taken to resus, and the intensive care team is called to review her. She is now severely hypoxic and has become confused. A decision is made to intubate the patient.